Data update as of 31/12/2023


6.1.5. GRUPO ASOCIADO DE ONCOLOGÍA RADIOTERÁPICA-220620-FOTO-web retocada6.1.5. GRUPO ASOCIADO DE ONCOLOGÍA RADIOTERÁPICA-220620-FOTO-web retocada2023 DATA

Person in charge


Research

  • Clinical

Location

Radiation Oncology Area, Floor -1.

Hospital Fundación Jiménez Díaz.

Avda. Reyes Católicos, 2. 28040 Madrid (España).


Key words

Radiation Oncology. Technological Advances. Therapeutic index. Radiobiology models. Intensity modulated radiation therapy (IMRT). Intensity volumetric modulated arc therapy (VMAT). Stereotactic brain radiotherapy (radiosurgery). Stereotactic body radiation therapy (SBRT). Surface guided radiation therapy (SGRT). 3D conformal radiation therapy (RTC3D). Image guided radiation therapy (IGRT). High rate brachytherapy. Radiomics. Self-segmentation.

Gender perspective

6.1.5-ONC RAD-GÉNERO6.1.5-ONC RAD-GÉNERO


Activity summary

Radiation Oncology is a medical specialty, with a specific scope in multidisciplinary management environments, dedicated to diagnostic aspects, clinical care, and more specifically therapeutic care of the oncological patient, primarily oriented to the use of radiation treatments and associated treatments. It is therefore a branch of clinical medicine that uses ionising radiation, alone or in combination with other therapeutic modalities, for the treatment of cancer and sometimes other non-neoplastic diseases.


Contributions to society

All the scientific activity of the Radiation Oncology group is directly oriented towards benefitting the patient and society. In recent years, advances in information technology have allowed for remarkable technological developments in terms of precision in radiotherapy treatments, such as three-dimensional imaging, auto-segmentation of organs at risk, and image guided (IGRT) and surface guided radiotherapy (SGRT), which improve the quality of the treatments performed. This improvement in precision has made it possible to administer high doses per fraction, adjusting the prescribed dose to the target volume, better preserving adjacent healthy tissues with resulting benefits for the patient. Likewise, treatment times have been reduced from 28-30 sessions to 3-10 sessions, and the biological efficacy of treatment has been increased.


Collaborations

  • Medical Oncology:
    • Therapeutic combinations with new drugs, target treatments and new radiosensitisers can be used in the local management of cancer. There are programmes with new generation immunotherapeutic agents in lung carcinoma.
    • Combinations of chemotherapeutics, such as trabectidine in combination with radiotherapy in the multidisciplinary management of soft tissue sarcomas.
  • Predictors of response to assess the efficacy of treatments for certain pathologies such as radiomics in carcinoma of the rectum or lung.
  • Multidisciplinary management in combination with medical oncology, radiology and digestive surgery in the conservation and conservative management of rectal cancer.
  • With systems to automate processes and improve therapeutic efficiency and safety.

PhD Theses

6.1.5-ONC RAD-TESIS6.1.5-ONC RAD-TESIS

List of publications ordered by publication date

Comparative effectiveness of new treatment modalities for localized prostate cancer through patient-reported outcome measures.

Zamora V, Garin O, Suárez JF, Gutiérrez C, Guedea F, Cabrera P, Castells M, Herruzo I, Fumadó L, Samper P, Ferrer C, Regis L, Pont À, Ferrer M, Multicentric Spanish Group of Clinically Localized Prostate Cancer.

Clin Transl Radiat Oncol. 2024 Jan.44:100694.

PMID: 38021091

FI: 3,1


Role of Radiotherapy and Hormone Therapy in Patients with Node-Positive Locally Advanced Prostate Cancer.

Amaya E, Carrasco E, López M, Gómez-Aparicio MA, Pelari-Mici L, Duque-Santana V, Zafra J, Achard V, Sargos P, López Campos F, Couñago F.

Arch Esp Urol. 2023 Dec.76(10):718-732.

PMID: 38186065

FI: 0,5


Psychometric validation of the Spanish version of the Expanded Prostate Cancer Index Composite-26.

Zamora V, Garin O, Suárez JF, Jové J, Castells M, Ferrer F, Gutiérrez C, Guedea F, Boladeras A, Fumadó L, Roselló A, Pastor J, Samper P, Pont À, Ferrer M.

World J Urol. 2023 Dec.41(12):3511-3518.

PMID: 37947846

FI: 3,4


Coronavirus disease 2019 and lung cancer: where are we?

Ocanto A, Mielgo-Rubio X, Luna Tirado J, Linares Mesa N, López Valcárcel M, Pedraza S, Barragan VV, Nieto PV, Martín JZ, Couñago F.

Explor Target Antitumor Ther. 2023.4(5):1082-1094.

PMID: 38023992

FI: 0


Management of non-hepatic distant metastases in neuroendocrine neoplasms.

Lacalle-González C, Estrella Santos A, Landaeta Kancev LC, Castellano VM, Macia Palafox E, Paniagua Ruíz A, Luna Tirado J, Martínez-Amores B, Martínez Dhier L, Lamarca A.

Best Pract Res Clin Endocrinol Metab. 2023 May 10:101784.

PMID: 37270333

FI: 7,4


Role of radiotherapy in the management of spine metastases.

Díaz Silvera CM, Azinovic I, Bolle SLE, Pérez Cobos M, Matute R.

Rev Esp Cir Ortop Traumatol. 2023 May 26.

PMID: 37245636

FI: 0

Projects, Contracts and Observational Studies

PUBLIC

Sources of public funding for projects being developed at the IIS-FJD:

_FUENTES DE FINANCIACIÓN PÚBLICA-02_FUENTES DE FINANCIACIÓN PÚBLICA-02

NA

PRIVATE

REFERENCE

PROJECT TITLE

PRINCIPAL RESEARCHER

TYPE OF PROJECT

6634/002

SOPORTE Y APOYO A LA LÍNEA DE INVESTIGACIÓN: IMPACTO DEL TRATAMIENTO DE RADIOTERAPIA SOBRE EL ESTADO NUTRICIONAL Y LA CAPACIDAD FUNCIONAL EN LOS MAYORES DE 70 AÑOS.

SAMPER OTS PILAR

PROYECTOS PRIVADOS NO COMPETITIVOS


Clinical trials

The clinical trials listed below were in the recruitment phase in 2023. If you are interested in participating in any of the currently open trials, more information is available on the website (https://ensayos.quironsalud.es/)

EudraCT Number

TITLE

PHASE

MC1

INT2

PRINCIPAL RESEARCHER

2021-006975-41

TERAPIA DE DEPRIVACION ANDROGENICA DE CORTA O LARGA DURACION EN COMBINACION CON RADIOTERAPIA DE RESCATE EN PACIENTES CON CANCER DE PROSTATA CON RECIDIVA BIOQUIMICA TRAS CIRUGIA: UN ENSAYO FASE III ALEATORIZADO, CONTROLADO, MULTICENTRICO

III

NO

NO

OLIVERA VEGAS JESUS

NA

START-MET HS PROSTATE CANCER: SBRT & ANDROGEN RECEPTOR THERAPY METASTATIC HSPC - (NA)

III

NO

NO

SAMPER OTS PILAR

MC1: Multicéntrico INT2: Internacional