Preventive Medicine-Public Health and Primary Care Associated Group

Activity summary

Contribute to the provision of personalised healthcare through Epidemiology and Public Health strategies. Its activities are geared towards Epidemiology, Health Protection and Promotion, Disease Prevention and the improvement of individual and collective health, Patient Safety and the improvement of Healthcare Quality. It also promotes activities related to research ethics, the principles of scientific integrity and good research practices. The members of the group participate in various teaching activities (undergraduate and graduate).

Contributions to society

The Preventive Medicine-Public Health and Primary Care group has a profile clearly geared towards improving care for society by reducing risks in medical care, improving resource use and contributing to evidence-based care, all with the ultimate goal of providing better care for patients and the community. In addition, it carries out training and dissemination activities related to the principles of research ethics, scientific integrity, and good research practices, with the aim of guaranteeing quality, reproducible scientific activity, with respect for the rights of research participants and the trust of society.

Collaborations

NA

PhD Theses

6.6.5-MED PREV AT PRIM-TESIS

List of publications ordered by publication date

Fundoplication with extensive dissection of the esophagogastric junction: Lessons learned and outcomes from 178 consecutives patients.

Salcedo Cabañas G, Martin Rios MD, Posada González M, Barragan Serrano C, Serrano Yébenes E, García Olmo D, Vorwald P.

Cir Esp (Engl Ed). 2023 Dec 21.

PMID: 38141845

FI: 1,9

Interobserver reliability of classifying shoulder calcific tendinopathy on plain radiography and ultrasound.

Fernández-Bravo Rueda A, Gutiérrez-San José B, Fernández-Jara J, Fernández-López A, Núñez de Aysa P, González-Martín D, Calvo E, Martín-Ríos MD.

Rev Esp Cir Ortop Traumatol. 2023 Dec 16.

PMID: 38110150

FI: 0

Clustering long-term health conditions among 67728 people with multimorbidity using electronic health records in Scotland.

Fagbamigbe AF, Agrawal U, Azcoaga-Lorenzo A, MacKerron B, Özyiğit EB, Alexander DC, Akbari A, Owen RK, Lyons J, Lyons RA, Denaxas S, Kirk P, Miller AC, Harper G, Dezateux C, Brookes A, Richardson S, Nirantharakumar K, Guthrie B, Hughes L, Kadam UT, Khunti K, Abrams KR, McCowan C.

PLoS One. 2023.18(11):e0294666.

PMID: 38019832

FI: 3,7

Prevalence and demographic variation of cardiovascular, renal, metabolic, and mental health conditions in 12 million english primary care records.

Cooper J, Nirantharakumar K, Crowe F, Azcoaga-Lorenzo A, McCowan C, Jackson T, Acharya A, Gokhale K, Gunathilaka N, Marshall T, Haroon S.

BMC Med Inform Decis Mak. 2023 Oct 16.23(1):220.

PMID: 37845709

FI: 3,5

Detection and evaluation of signals associated with exposure to individual and combination of medications in pregnancy: a signal detection study protocol.

Subramanian A, Lee SI, Hemali Sudasinghe SPB, Wambua S, Phillips K, Singh M, Azcoaga-Lorenzo A, Cockburn N, Wang J, Fagbamigbe A, Usman M, Damase-Michel C, Yau C, Kent L, McCowan C, OReilly D, Santorelli G, Hope H, Kennedy J, Mhereeg M, Abel KM, Eastwood KA, Black M, Loane M, Moss N, Brophy S, Brocklehurst P, Dolk H, Nelson-Piercy C, Nirantharakumar K, MuM-PreDiCT Group.

BMJ Open. 2023 Oct 09.13(10):e073162.

PMID: 37813531

FI: 2,9

Posting of clinical trial results and other critical information from completed medicines trials on ClinicalTrials.gov.

Dal-Ré R, Mahillo-Fernández I.

Eur J Clin Pharmacol. 2023 Oct.79(10):1385-1390.

PMID: 37581640

FI: 2,9

Maternal multimorbidity and preterm birth in Scotland: an observational record-linkage study.

Azcoaga-Lorenzo A, Fagbamigbe AF, Agrawal U, Black M, Usman M, Lee SI, Eastwood KA, Moss N, Plachcinski R, Nelson-Piercy C, Brophy S, O'Reilly D, Nirantharakumar K, McCowan C, MuM-PreDiCT Group.

BMC Med. 2023 Sep 12.21(1):352.

PMID: 37697325

FI: 9,3

COVID-19 vaccination in pregnancy: the impact of multimorbidity and smoking status on vaccine hesitancy, a cohort study of 25,111 women in Wales, UK.

Mhereeg M, Jones H, Kennedy J, Seaborne M, Parker M, Kennedy N, Akbari A, Zuccolo L, Azcoaga-Lorenzo A, Davies A, Nirantharakumar K, Brophy S.

BMC Infect Dis. 2023 Sep 11.23(1):594.

PMID: 37697235

FI: 3,7

Trajectories in chronic disease accrual and mortality across the lifespan in Wales, UK (2005-2019), by area deprivation profile: linked electronic health records cohort study on 965,905 individuals.

Lyons J, Akbari A, Abrams KR, Azcoaga Lorenzo A, Ba Dhafari T, Chess J, Denaxas S, Fry R, Gale CP, Gallacher J, Griffiths LJ, Guthrie B, Hall M, Jalali-Najafabadi F, John A, MacRae C, McCowan C, Peek N, O'Reilly D, Rafferty J, Lyons RA, Owen RK.

Lancet Reg Health Eur. 2023 Sep.32:100687.

PMID: 37520147

FI: 20,9

Leading pharmaceutical companies lacked transparency on clinical trials' informed consent forms.

Dal-Ré R, Voo TC, Holm S.

J Clin Epidemiol. 2023 Aug 28.

PMID: 37648072

FI: 7,2

Is current UK transparency on clinical trials enough?

Dal-Ré R.

BMJ. 2023 Aug 22.382:1933.

PMID: 37607740

FI: 107,7

The development of a core outcome set for studies of pregnant women with multimorbidity.

Lee SI, Hanley S, Vowles Z, Plachcinski R, Moss N, Singh M, Gale C, Fagbamigbe AF, Azcoaga-Lorenzo A, Subramanian A, Taylor B, Nelson-Piercy C, Damase-Michel C, Yau C, McCowan C, O'Reilly D, Santorelli G, Dolk H, Hope H, Phillips K, Abel KM, Eastwood KA, Kent L, Locock L, Loane M, Mhereeg M, Brocklehurst P, McCann S, Brophy S, Wambua S, Hemali Sudasinghe SPB, Thangaratinam S, Nirantharakumar K, Black M, MuM-PreDiCT Group.

BMC Med. 2023 Aug 21.21(1):314.

PMID: 37605204

FI: 9,3

Key outcomes for reporting in studies of pregnant women with multiple long-term conditions: a qualitative study.

Lee SI, Hanley S, Vowles Z, Plachcinski R, Azcoaga-Lorenzo A, Taylor B, Nelson-Piercy C, McCowan C, O'Reilly D, Hope H, Abel KM, Eastwood KA, Locock L, Singh M, Moss N, Brophy S, Nirantharakumar K, Thangaratinam S, Black M.

BMC Pregnancy Childbirth. 2023 Aug 01.23(1):551.

PMID: 37528358

FI: 3,1

Using the phases of clinical development of medicines to describe clinical trials assessing other interventions is widespread but not useful.

Dal-Ré R, Banzi R, Cristea IA, Fernández-de-Las-Peñas C, Hemkens LG, Janiaud P, Jansen MS, Naudet F, Rosendaal FR.

J Clin Epidemiol. 2023 Jul 28.

PMID: 37517503

FI: 7,2

COVID-19 research waste: An analysis on terminated clinical trials on medicines on ClinicalTrials.gov.

Dal-Ré R.

Eur J Intern Med. 2023 Jul 26.

PMID: 37507265

FI: 8

Effect on life expectancy of temporal sequence in a multimorbidity cluster of psychosis, diabetes, and congestive heart failure among 1·7 million individuals in Wales with 20-year follow-up: a retrospective cohort study using linked data.

Owen RK, Lyons J, Akbari A, Guthrie B, Agrawal U, Alexander DC, Azcoaga-Lorenzo A, Brookes AJ, Denaxas S, Dezateux C, Fagbamigbe AF, Harper G, Kirk PDW, Özyiğit EB, Richardson S, Staniszewska S, McCowan C, Lyons RA, Abrams KR.

Lancet Public Health. 2023 Jul.8(7):e535-e545.

PMID: 37393092

FI: 50

"'Pragmatic' or 'streamlined': Which term best fits the REMAP-CAP trial.

Dal-Ré R.

Eur J Intern Med. 2023 Jul.113:119-121.

PMID: 37030996

FI: 8

Researchers Forget to Report How to Share Data From Studies Published in Spanish Medical Journals.

Dal-Ré R.

Arch Bronconeumol. 2023 Jul.59(7):461-463.

PMID: 36872210

FI: 8

Clinical Evolution and Risk Factors in Patients Infected during the First Wave of COVID-19: A Two-Year Longitudinal Study.

Rescalvo-Casas C, Pérez-Tanoira R, Villegas RF, Hernando-Gozalo M, Seijas-Pereda L, Pérez-García F, Moríñigo HM, Gómez-Herruz P, Arroyo T, González R, Expósito CV, Lledó García L, Cabrera JR, Cuadros-González J.

Trop Med Infect Dis. 2023 Jun 25.8(7).

PMID: 37505636

FI: 2,9

Is the TIME study on antihypertensive therapy and chronotropic effects on cardiovascular outcomes a pragmatic trial?

Dal-Ré R, James SK.

Eur Heart J Cardiovasc Pharmacother. 2023 Jun 02.9(4):399-400.

PMID: 36893805

FI: 7,1

Is it reasonable to label a trial as pragmatic whose investigators do not? The UK RECOVERY COVID-19 trial case.

Dal-Ré R.

Clin Trials. 2023 Jun.20(3):319-321.

PMID: 36740750

FI: 2,7

Adaptive, platform trials assessing therapies for hospitalized COVID-19 patients: Informed consent forms omitted a few important elements of information.

Dal-Ré R, Voo TC, Holm S.

J Glob Health. 2023 May 12.13:06019.

PMID: 37166268

FI: 7,2

Using artificial intelligence to reduce orthopedic surgical site infection surveillance workload: Algorithm design, validation, and implementation in 4 Spanish hospitals.

Flores-Balado Á, Castresana Méndez C, Herrero González A, Mesón Gutierrez R, de Las Casas Cámara G, Vila Cordero B, Arcos J, Pfang B, Martín-Ríos MD, Surgical Site Infection Surveillance Group.

Am J Infect Control. 2023 Apr 24.

PMID: 37100291

FI: 4,9

Waivers of informed consent in research with competent participants and the Declaration of Helsinki.

Dal-Ré R.

Eur J Clin Pharmacol. 2023 Apr.79(4):575-578.

PMID: 36884061

FI: 2,9

Prevalence of polypharmacy in pregnancy: a systematic review.

Anand A, Phillips K, Subramanian A, Lee SI, Wang Z, McCowan R, Agrawal U, Fagbamigbe AF, Nelson-Piercy C, Brocklehurst P, Damase-Michel C, Loane M, Nirantharakumar K, Azcoaga-Lorenzo A, MuM-PreDiCT Group.

BMJ Open. 2023 Mar 06.13(3):e067585.

PMID: 36878655

FI: 2,9

Maternal and child outcomes for pregnant women with pre-existing multiple long-term conditions: protocol for an observational study in the UK.

Lee SI, Hope H, O'Reilly D, Kent L, Santorelli G, Subramanian A, Moss N, Azcoaga-Lorenzo A, Fagbamigbe AF, Nelson-Piercy C, Yau C, McCowan C, Kennedy JI, Phillips K, Singh M, Mhereeg M, Cockburn N, Brocklehurst P, Plachcinski R, Riley RD, Thangaratinam S, Brophy S, Hemali Sudasinghe SPB, Agrawal U, Vowles Z, Abel KM, Nirantharakumar K, Black M, Eastwood KA, MuM-PreDiCT.

BMJ Open. 2023 Feb 24.13(2):e068718.

PMID: 36828655

FI: 2,9

How WHO Solidarity Plus trial participants in countries on four continents are informed in writing.

Dal-Ré R, Voo TC, Holm S.

J Glob Health. 2023 Jan 20.13:04012.

PMID: 36655916

FI: 7,2

Polypharmacy during pregnancy and associated risk factors: a retrospective analysis of 577 medication exposures among 1.5 million pregnancies in the UK, 2000-2019.

Subramanian A, Azcoaga-Lorenzo A, Anand A, Phillips K, Lee SI, Cockburn N, Fagbamigbe AF, Damase-Michel C, Yau C, McCowan C, O'Reilly D, Santorelli G, Hope H, Kennedy JI, Abel KM, Eastwood KA, Locock L, Black M, Loane M, Moss N, Plachcinski R, Thangaratinam S, Brophy S, Agrawal U, Vowles Z, Brocklehurst P, Dolk H, Nelson-Piercy C, Nirantharakumar K, MuM-PreDiCT Group.

BMC Med. 2023 Jan 16.21(1):21.

PMID: 36647047

FI: 9,3

Reply to ""Olfactory Function and Biologic Treatments: A Comment on Available Real-life Studies"".

Barroso B, Valverde-Monge M, Alobid I, Olaguibel JM, Rial MJ, Quirce S, Arismendi E, Barranco P, Betancor D, Bobolea I, Cárdaba B, Cruz Carmona MJ, Curto E, Domínguez-Ortega J, González-Barcala FJ, Martínez-Rivera C, Mahíllo-Fernández I, Muñoz X, Picado C, Plaza V, Rodrigo Muñoz JM, Soto-Retes L, Valero A, Del Pozo V, Mullol J, Sastre J.

J Investig Allergol Clin Immunol. 2023 Dec.33(6):503-504.

PMID: 38095497

FI: 7,2

Sex-dependent relationship of polymorphisms in CLOCK and REV-ERBα genes with body mass index and lipid levels in children.

Vales-Villamarín C, de Dios O, Mahíllo-Fernández I, Perales M, Pérez-Nadador I, Gavela-Pérez T, Soriano-Guillén L, Garcés C.

Sci Rep. 2023 Dec 13.13(1):22127.

PMID: 38092833

FI: 4,6

HLA-A*11:01 and HLA-C*04:01 are associated with severe COVID-19.

Castro-Santos P, Rojas-Martinez A, Riancho JA, Lapunzina P, Flores C, Carracedo Á, Díaz-Peña R; Scourge Cohort Group (Llanos L, Almoguera B, Ayuso C, Corton M, Mínguez P, Mahillo-Fernández I, Zazo S, Rojo F, Gadea I, Sarah Heili-Frades,Sanchez-Pernaute O).

HLA. 2023 Dec;102(6):731-739.

PMID: 37528566

FI: 8

Comparison of Long-term Response and Remission to Omalizumab and Anti-IL-5/IL-5R Using Different Criteria in a Real-life Cohort of Severe Asthma Patients.

Valverde-Monge M, Sánchez-Carrasco P, Betancor D, Barroso B, Rodrigo-Muñoz JM, Mahillo-Fernández I, Arismendi E, Bobolea I, Cárdaba B, Cruz MJ, Del Pozo V, Domínguez-Ortega J, González-Barcala FJ, Olaguibel JM, Luna-Porta JA, Martínez-Rivera C, Mullol J, Muñoz X, Peleteiro-Pedraza L, Picado Valles C, Plaza V, Quirce S, Rial MJ, Soto-Retes L, Valero A, Sastre J.

Arch Bronconeumol. 2023 Nov 22.

PMID: 38042707

FI: 8

Patient Characteristics Associated with Growth of Patient-Derived Tumor Implants in Mice (Patient-Derived Xenografts).

Hernández Guerrero T, Baños N, Del Puerto Nevado L, Mahillo-Fernandez I, Doger De-Speville B, Calvo E, Wick M, García-Foncillas J, Moreno V.

Cancers (Basel). 2023 Nov 14.15(22).

PMID: 38001663

FI: 5,2

Fibroblast growth factor 23 independently predicts adverse outcomes after an acute coronary syndrome.

Kallmeyer A, Pello A, Cánovas E, Aceña Á, González-Casaus ML, Tarín N, Cristóbal C, Gutiérrez-Landaluce C, Huelmos A, Rodríguez-Valer A, González-Lorenzo Ó, Alonso J, López-Bescós L, Egido J, Mahillo I, Lorenzo Ó, Tuñón J.

ESC Heart Fail. 2023 Nov 10.

PMID: 37950429

FI: 3,8

Effects of usual yoga practice on the diaphragmatic contractility: A cross-sectional controlled study.

Fernández-Pardo TE, Furió-Valverde M, García-Arrabé M, Valcárcel-Linares D, Mahillo-Fernández I, Peces-Barba Romero G.

Heliyon. 2023 Oct.9(10):e21103.

PMID: 37916088

FI: 4

Osteoporotic vertebral fractures localized in the lumbar area significantly impact sagittal alignment.

Plais N, Bustos JG, Mahillo-Fernández I, Tomé-Bermejo F, Mengis C, Alvarez-Galovich L.

Osteoporos Int. 2023 Oct 13.

PMID: 37833542

FI: 4

Frailty assessment to individualize treatment in older patients with lymphoma.

Hormigo-Sanchez AI, Lopez-Garcia A, Mahillo-Fernandez I, Askari E, Morillo D, Perez-Saez MA, Riesco M, Urrutia C, Martinez-Peromingo FJ, Cordoba R, Gonzalez-Montalvo JI.

Eur Geriatr Med. 2023 Oct 12.

PMID: 37823983

FI: 3,8

Postnatal catch-up growth in term newborns with altered fetal weight patterns. The GROWIN study.

Galán Arévalo MS, Mahillo-Fernández I, Saenz De Pipaon M, Esteban LM, Hernández Martín D, Rodriguez Delgado J, Estevez Muñoz JC, Andeyro-García M, Piñeiro Perez R, Savirón-Cornudella R.

Pediatr Res. 2023 Apr 17.

PMID: 37069223

FI: 3,6

Enhanced thrombin generation detected with ST-Genesia analyzer in patients with newly diagnosed multiple myeloma.

Velasco-Rodríguez D, Martínez-Alfonzo I, Velasco-Valdazo AE, Revilla N, Mahíllo-Fernández I, Askari E, Castro-Quismondo N, Laso RV, Domingo-González A, Serrano-López J, Prieto E, Rosado B, Blanchard MJ, Martín-Herrero S, García-Raso A, Bueno MÁ, de la Plaza R, Peñaherrera M, López IG, López-Jiménez J, Martínez-López J, Llamas-Sillero P.

J Thromb Thrombolysis. 2023 Apr.55(3):464-473.

PMID: 36630029

FI: 4

ADAM10 Gene Variants in AD Patients and Their Relationship to CSF Protein Levels.

Agüero-Rabes P, Pérez-Pérez J, Cremades-Jimeno L, García-Ayllón MS, Gea-González A, Sainz MJ, Mahillo-Fernández I, Téllez R, Cárdaba B, Sáez-Valero J, Gómez-Tortosa E.

Int J Mol Sci. 2023 Mar 24.24(7).

PMID: 37047093

FI: 5,6

Analysis of Differentially Expressed MicroRNAs in Serum and Lung Tissues from Individuals with Severe Asthma Treated with Oral Glucocorticoids.

Gil-Martínez M, Lorente-Sorolla C, Rodrigo-Muñoz JM, Lendínez MÁ, Núñez-Moreno G, de la Fuente L, Mínguez P, Mahíllo-Fernández I, Sastre J, Valverde-Monge M, Quirce S, Caballero ML, González-Barcala FJ, Arismendi E, Bobolea I, Valero A, Muñoz X, Cruz MJ, Martínez-Rivera C, Plaza V, Olaguibel JM, Del Pozo V.

Int J Mol Sci. 2023 Jan 13.24(2).

PMID: 36675122

FI: 5,6

Decrease in Readmissions after Hospitalisation for COPD Exacerbation through a Home Care Model.

Sánchez-Mellado D, Villar-Álvarez F, Fernández Ormaechea I, Naya Prieto A, Armenta Fernández R, Gómez Del Pulgar Murcia T, Mahillo-Fernández I, Peces-Barba Romero G.

Open Respir Arch. 2022.4(3):100190.

PMID: 37496576

FI: 0

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.

Pairo-Castineira E, Rawlik K, Bretherick AD, Qi T, Wu Y, Nassiri I, McConkey GA, Zechner M, Klaric L, Griffiths F, Oosthuyzen W, Kousathanas A, Richmond A, Millar J, Russell CD, Malinauskas T, Thwaites R, Morrice K, Keating S, Maslove D, Nichol A, Semple MG, Knight J, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Begg C, Walsh T, Tenesa A, Flores C, Riancho JA, Rojas-Martinez A, Lapunzina P; GenOMICC Investigators; SCOURGE Consortium; ISARICC Investigators; 23andMe COVID-19 Team; Yang J, Ponting CP, Wilson JF, Vitart V, Abedalthagafi M, Luchessi AD, Parra EJ, Cruz R, Carracedo A, Fawkes A, Murphy L, Rowan K, Pereira AC, Law A, Fairfax B, Hendry SC, Baillie JK. (Llanos L, Ayuso C, Gadea I, Sarah Heili-Frades, Sanchez-Pernaute O).

Nature. 2023 May;617(7962):764-768.

PMID: 37198478

FI: 64,8