Infectious Disease and Tropical Medicine

6.2.2-ENF INFECC-GÉNERO

Activity summary

The main lines of research include basic and clinical studies on HIV infection, with special interest in researching the mechanisms of viral persistence; the factors underlying viral control; the role of chronic inflammation; HIV-cancer interactions; the testing of new antiretroviral treatments and vaccines against infection. There is also clinical research in other areas of infectious and tropical diseases.

Contributions to society

The group actively collaborates with associations that help patients with HIV infection and in the prevention of its acquisition, carrying out joint research. It also collaborates with all informative initiatives on infectious diseases and with specific courses on the prevention of sexually transmitted infections.

Collaborations

The group actively collaborates both with intramural groups in all the centers that are part of the IIS-FJD, as well as with external groups both nationally and internationally. These include collaboration with: the Center for Virus Research at the Westmead Institute for Medical Research in the Faculty of Medicine and Health at the University of Sydney in Australia; the Faculty of Medicine at the UPTC Pedagogical and Technological University in Colombia; the Immunogenetics Unit of the Department of Experimental Biology at the University of Jaén; the CAI of Biological Techniques at the Complutense de Madrid University; the Institute of Biomedicine of Cordoba (IMIBIC) and Cordoba Science and Technology Park; the National Microbiology Center-ISCIII in Majadahonda-Madrid; the Proteomics Unit of the CNIC in Madrid; the National Cancer Research Center, CNIO in Madrid; the Valle de Hebrón University Hospital in Barcelona; the National Electron Microscopy Center-ICTS- of the UCM in Madrid; the Madrid Science Park Foundation (UAM); the metabolomics and bioanalysis center of the San Pablo CEU University in Madrid; the Bioinformatics Unit of the CNIC in Madrid. Other relevant collaborations of the group include: the Autonomous University of Madrid, directing and coordinating the Master in Tropical Medicine and International Health; the Miguel Hernández de Alicante University, participating in teaching and research activities in tropical diseases; the Virgen del Loreto Hospital (Iquitos, Peru) and the Rural Hospital of Gambo (Ethiopia), in research on tropical infectious diseases.

PhD Theses

6.2.2-ENF INFECC-TESIS

List of publications ordered by publication date

Immune checkpoint inhibitors as potential therapy for reverting T-cell exhaustion and reverting HIV latency in people living with HIV.

Benito JM, Restrepo C, García-Foncillas J, Rallón N.

Front Immunol. 2023.14:1270881.

PMID: 38130714

FI: 7,3

Prevalence of Chagas disease in Latin American pregnant women in Madrid, Spain: A multicentre cross-sectional study from 2011 to 2016.

Herrero-Martínez JM, Trigo E, Navarro M, García-Alcázar D, Carrillo I, Fernández-López T, Calderón-Moreno M, Millán-Pérez R, Cuadros J, Velasco M, García-Bujalance S, Lizasoain M, Martín-Rabadán P, Pérez-Ayala A, Flores-Chávez M, Working Group on Chagas Disease of Madrid.

Trop Med Int Health. 2023 Dec.28(12):912-922.

PMID: 37905331

FI: 3,3

Patterns of Sexualized Drug Use among Gay, Bisexual, and Other Men Who Have Sex with Men Living with HIV: Insights from a Comprehensive Study-The U-SEX-2 GESIDA 9416 Study.

Ryan P, Dolengevich-Segal H, Ramos-Ruperto L, Cabello A, Sanchez-Conde M, Vergas J, Valencia J, Cuevas G, Sanz J, Curto-Ramos J, Pérez-Bootello J, Naharro-Rodriguez J, Ollero MJF, Garcia Fraile L, Pérez-Latorre L, Bisbal O, De la Fuente S, Losa JE, Cervero M, Estebanez M, Suarez-Garcia I, Gimeno A, Terrancle I, Mican R, González-Baeza A, U-Sex Gesida 9416 Study.

J Clin Med. 2023 Nov 24.12(23).

PMID: 38068345

FI: 3,9

Recently acquired hepatitis C: Epidemiological characteristics and treatment response in a large cohort of MSM living with HIV in Madrid.

Martín-Carbonero L, Gutierrez Á, Bisbal O, Vergas J, González-Baeza A, Rodríguez Martín C, Vivancos MJ, Sanz J, Álvarez B, Palomar M, de Los Santos I, Sepúlveda-Crespo D, Resino S, Berenguer J, Cano-Smith J, González-García J, Ryan P.

Enferm Infecc Microbiol Clin (Engl Ed). 2023 Nov 07.

PMID: 37945463

FI: 0

IL7RA rs10491434 polymorphism is related to spontaneous HIV infection control in naïve HIV-infected patients: A retrospective study.

Sepúlveda-Crespo D, Jiménez-Sousa MA, Fernández-Rodíguez A, Muñoz-Fernández MA, Jiménez JL, Caraciolo BB, Reus Bañuls S, Vilchez H, Mothe B, Martínez I, Benito JM, Rallón N, Resino S.

J Med Virol. 2023 Nov.95(11):e29214.

PMID: 37927108

FI: 12,7

EUS-guided gallbladder drainage as second option of biliary decompression after failed ERCP for the management of malignant distal biliary obstruction.

Chavarría Herbozo CM, Sancho-Del Val L, Cuadrado-Tiemblo C, Vicente Martín C, Wong Becerra L, Riado Mínguez D.

Rev Esp Enferm Dig. 2023 Oct 26.

PMID: 37882194

FI: 2

Demographic study of persons living with HIV (PLWH) newly diagnosed in the healthcare area of a tertiary-level hospital.

Al-Hayani AW, Cabello-Ubeda A, Ramírez Verdyguer M, Téllez Pérez R, Castaño Núñez ÁL, de Górgolas Hernández-Mora M.

Semergen. 2023 Oct 10.50(1):102088.

PMID: 37827046

FI: 1,1

Frailty assessment to individualize treatment in older patients with lymphoma.

Hormigo-Sanchez AI, Lopez-Garcia A, Mahillo-Fernandez I, Askari E, Morillo D, Perez-Saez MA, Riesco M, Urrutia C, Martinez-Peromingo FJ, Cordoba R, Gonzalez-Montalvo JI.

Eur Geriatr Med. 2023 Oct 12.

PMID: 37823983

FI: 3,8

The caregiver's perspective on end-of-life inpatient palliative care: a qualitative study.

Herrera-Abián M, Castañeda-Vozmediano R, Antón-Rodríguez C, Palacios-Ceña D, González-Morales LM, Pfang B, Noguera A.

Ann Med. 2023.55(2):2260400.

PMID: 37738527

FI: 4,4

Diagnostic and Management Strategies of Tubulointerstitial Nephritis and Uveitis Syndrome (TINU): Current Perspectives.

Sanchez-Quiros J, Giralt L, Fonollosa A, Robles I, Carreño E.

Clin Ophthalmol. 2023.17:2625-2630.

PMID: 37701464

FI: 2,2

Vaccination trends in people with HIV infection participanting in the hospital-based survey of patients infected with HIV, 2006-2021.

Hernando V, Suárez L, Gutiérrez G, López JC, Navarro-Soler R, Cabello A, Sanz J, Suarez-García I, Fernández MT, Losa JE, Pérez JL, Ramos-Ruperto L, Pérez-Elías MJ, Aayuni WBCE, Cuesta M, González G, Izquierdo A, Viloria L, López I, Martínez E, Castrillejo D, Jaume Amengual MG, Belmonte MA, Arraiza A, de la Torre J, Miqueleiz E, Marcos H, Ruiz-Algueró M, Villegas T, Simón L, Diaz A, Hospital Survey Working Group.

Enferm Infecc Microbiol Clin (Engl Ed). 2023 Aug 10.

PMID: 37573244

FI: 0

Medical nutrition therapy in patients receiving extracorporeal membrane oxygenation: knowledge in progress.

Robledo-Valdez M, Carrera-Quintanar L, Morante-Ruiz M, Pérez-de-Acha-Chávez A, Cervantes-Guevara G, Cervantes-Cardona GA, Torres-Mendoza BM, Ramírez-Ochoa S, Cervantes-Pérez G, González-Ojeda A, Fuentes-Orozco C, Cervantes-Pérez E.

Arch Cardiol Mex. 2023.93(3):348-354.

PMID: 37562137

FI: 0,5

Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Intravenous Infusions of PF-07304814 (Lufotrelvir) in Participants Hospitalized With COVID-19.

Robinson P, Toussi SS, Aggarwal S, Bergman A, Zhu T, Hackman F, Sathish JG, Updyke L, Loudon P, Krishna G, Clevenbergh P, Hernandez-Mora MG, Cisneros Herreros JM, Albertson TE, Dougan M, Thacker A, Baniecki ML, Soares H, Whitlock M, Nucci G, Menon S, Anderson AS, Binks M.

Open Forum Infect Dis. 2023 Aug.10(8):ofad355.

PMID: 37559753

FI: 4,2

Incidence of Anal Cancer and Related Risk Factors in HIV-Infected Patients Enrolled in the National Prospective Spanish Cohort CoRIS.

Cudós ES, De La Piedra CS, Canuto MM, Úbeda AC, Curran A, Hermida AO, Rava M, Muriel A, Macías J, Rial-Crestelo D, Martínez-Sanz J, Martinez L, De La Villa López-Sánchez M, Perez-Molina JA.

Dis Colon Rectum. 2023 Aug 03.

PMID: 37556018

FI: 4,1

Hemophagocytic Lymphohistiocytosis Secondary to Hodgkin's Lymphoma with Isolated Bone Marrow Involvement in a Newly Diagnosed HIV Patient.

Lopez-Garcia A, Solan L, Alvarez B, Caballero JC, Cornago J, Pardo L, Diaz de la Pinta FJ, Cordoba R, Rodriguez-Pinilla M.

Medicina (Kaunas). 2023 Jul 09.59(7).

PMID: 37512086

FI: 2,6

Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer.

Serrano-Villar S, Tincati C, Raju SC, Sáenz JS, Moreno E, Bargiela R, Cabello-Ubeda A, Sendagorta E, Kurz A, Perez Molina JA, de Benito A, Hov JR, Fernandez-Lopez L, Muriel A, Del Campo R, Moreno S, Trøseid M, Seifert J, Ferrer M.

Nat Med. 2023 Jul.29(7):1738-1749.

PMID: 37464040

FI: 82,9

Expert Consensus: Main Risk Factors for Poor Prognosis in COVID-19 and the Implications for Targeted Measures against SARS-CoV-2.

Candel FJ, Barreiro P, Salavert M, Cabello A, Fernández-Ruiz M, Pérez-Segura P, San Román J, Berenguer J, Córdoba R, Delgado R, España PP, Gómez-Centurión IA, González Del Castillo JM, Heili SB, Martínez-Peromingo FJ, Menéndez R, Moreno S, Pablos JL, Pasquau J, Piñana JL, On Behalf Of The Modus Investigators Adenda.

Viruses. 2023 Jun 27.15(7).

PMID: 37515137

FI: 4,7

Assessing the Virologic Impact of Archived Resistance in the Dolutegravir/Lamivudine 2-Drug Regimen HIV-1 Switch Study TANGO through Week 144.

Wang R, Wright J, Saggu P, Ait-Khaled M, Moodley R, Parry CM, Lutz T, Podzamczer D, Moore R, Górgolas Hernández-Mora M, Kinder C, Wynne B, van Wyk J, Underwood M.

Viruses. 2023 Jun 11.15(6).

PMID: 37376649

FI: 4,7

Hypopyon Uveitis as a Manifestation of Primary Choroidal Lymphoma.

Vidal C, Robles I, Escamilla N, Losada D, Serrano C, Miranda C, Pastor AI, Carreño E.

Ocul Immunol Inflamm. 2023 Jun 21:1-3.

PMID: 37343273

FI: 3,3

IRF5-TNOP3 polymorphisms are associated with elite control of HIV infection: A retrospective study.

Sepúlveda-Crespo D, Jiménez-Sousa MA, Fernández-Rodíguez A, Muñoz-Fernández MA, Jiménez JL, Moreno S, Garcia F, Martínez I, Benito JM, Rallón N, Resino S.

J Med Virol. 2023 Jun.95(6):e28841.

PMID: 37254791

FI: 12,7

A Clinical-Genetic Risk Score for Predicting Cancer-Associated Venous Thromboembolism: A Development and Validation Study Involving Two Independent Prospective Cohorts.

Muñoz A, Ay C, Grilz E, López S, Font C, Pachón V, Castellón V, Martínez-Marín V, Salgado M, Martínez E, Calzas J, Ortega L, Rupérez A, Salas E, Pabinger I, Soria JM.

J Clin Oncol. 2023 Jun 01.41(16):2911-2925.

PMID: 36730884

FI: 45,4

Primary Effusion Lymphoma, Multicentric Castleman's Disease, and Kaposi's Sarcoma in an HHV-8 and HIV-Positive Patient: A Case Report.

Caballero JC, Pardo L, Rodriguez-Pinilla MS, Piris MA, Alvarez B, Solan L, Cornago J, Lopez-Lorenzo JL, Llamas P, Cordoba R, Lopez-Garcia A.

Medicina (Kaunas). 2023 May 30.59(6).

PMID: 37374253

FI: 2,6

Differences in Virulence Factors and Antimicrobial Susceptibility of Uropathogenic Enterococcus spp. Strains in a Rural Area of Uganda and a Spanish Secondary Hospital.

Carrasco Calzada F, Jairo Aguilera J, Moreno JE, Cuadros González J, Roca Biosca D, Prieto-Pérez L, Pérez-Tanoira R.

Trop Med Infect Dis. 2023 May 16.8(5).

PMID: 37235330

FI: 2,9

Increased Prevalence of Symptomatic Human Intestinal Spirochetosis in MSM with High-Risk Sexual Behavior in a Cohort of 165 Individuals.

Pérez-Tanoira R, Tamarit MDP, Montaña AMV, Carmena D, Köster P, Górgolas M, Fortes Alen JR, Cabello-Úbeda A, Prieto-Pérez L.

Trop Med Infect Dis. 2023 Apr 26.8(5).

PMID: 37235298

FI: 2,9

«When lack of protection brings us closer to our origins». The start of a pandemic.

Carrillo I, Velasco MJ, Fuertes de Vega L, Álvarez B.

Enferm Infecc Microbiol Clin (Engl Ed). 2023 Apr 26.

PMID: 37117144

FI: 0

Enterocytozoon bieneusi and Encephalitozoon intestinalis (microsporidia) in HIV-positive patients in central Spain.

Chozas M, Dashti A, Prieto-Pérez L, Pérez-Tanoira R, Cobo E, Bailo B, Del Palacio M, Hernández-Castro C, González-Barrio D, Carmena D, Köster PC.

Med Mycol. 2023 Apr 03.61(4).

PMID: 37024274

FI: 2,9

ADAM10 Gene Variants in AD Patients and Their Relationship to CSF Protein Levels.

Agüero-Rabes P, Pérez-Pérez J, Cremades-Jimeno L, García-Ayllón MS, Gea-González A, Sainz MJ, Mahillo-Fernández I, Téllez R, Cárdaba B, Sáez-Valero J, Gómez-Tortosa E.

Int J Mol Sci. 2023 Mar 24.24(7).

PMID: 37047093

FI: 5,6

Reflecting on oncogeriatrics: What can be done to promote the integration of the comprehensive geriatric assessment in the oncology practice?

González-Senac NM, Rodríguez-Couso M.

Rev Esp Geriatr Gerontol. 2023.58(2):121-122.

PMID: 36894380

FI: 0

Diagnosis and Management of Adult Tuberculosis Patients Admitted to a Rural Hospital in Ethiopia.

Comeche B, Pérez-Butragueño M, Górgolas M, Ramos-Rincón JM.

Cureus. 2023 Feb.15(2):e35519.

PMID: 37007370

FI: 0

Terapia médico-nutricional en pacientes politraumatizados: una carrera contra el tiempo.

Padilla-Rubio MF, Robledo-Valdez M, Morante-Ruiz M, Acha-Chávez AP, Cervantes-Guevara G, Cervantes-Cardona GA, Ramírez-Ochoa S, Cervantes-Pérez G, González-Ojeda A, Fuentes-Orozco C, Gómez-Sánchez E, Cervantes-Pérez E.

Cir Cir. 2023.91(1):122-130.

PMID: 36787600

FI: 0,5

Screening for hidden human immunodeficiency virus infection in the emergency department: one hospital's experience.

Del Palacio-Tamarit M, Sanz-Lorente R, Álvarez-Álvarez B, Cabello-Úbeda A, García-Cañete J, Blanco-García A.

Emergencias. 2023 Feb.35(1):74-75.

PMID: 36756920

FI: 5,5

Tubulointerstitial Nephritis and Uveitis Syndrome (TINU) after Intake of Dietary Supplement.

Vidal C, Robles I, Carreño E.

Ocul Immunol Inflamm. 2023 Jan 10:1-2.

PMID: 36628464

FI: 3,3

Effects of frailty, geriatric syndromes, and comorbidity on mortality and quality of life in older adults with HIV.

Brañas F, Torralba M, Antela A, Vergas J, Ramírez M, Ryan P, Dronda F, Galindo MJ, Machuca I, Bustinduy MJ, Cabello A, Montes ML, Sánchez-Conde M, FUNCFRAIL study group.

BMC Geriatr. 2023 Jan 03.23(1):4.

PMID: 36597036

FI: 4,1