Data update as of 31/12/2023


Area coordinators:



Foto1Foto1

This strategic area is made up of three groups and two associated groups, with strong ties between them. The Cardiology area recently established a very close relationship with the Carlos III National Center for Cardiovascular Research (CNIC), together carrying out experimental and clinical projects under a collaboration agreement.


Its objectives include:

  • The common objective of the research area is to deepen the understanding of damage and repair mechanisms in reno-urological, cardiovascular, metabolic and diabetic diseases, from childhood onwards. Within this common framework, each group and subgroup focuses on certain aspects, sharing techniques and knowledge to accelerate discovery and translate advances to the clinic.
  • Study the cellular and molecular mechanisms (fibrosis, immuno-inflammation, apoptosis, intracellular signalling, cytokines, renin-angiotensin system, etc.) involved in the pathogenesis of certain diseases (atherothrombosis, myocardial ischemia/reperfusion, cardiomyopathies, diabetic nephropathy, hypertension, glomerular pathology, acute renal failure, nephrotoxicity, obesity and diabetes, etc.).
  • Application of different platforms and imaging techniques (proteomics, genomics, metabolomics, cardiac magnetic resonance, molecular imaging, etc.) to the identification of new molecules with diagnostic or therapeutic potential in the aforementioned pathologies.
  • Discovery and preclinical development of new therapeutic approaches for clinical application in the prevention and/or treatment of these pathologies.

Furthermore, there is significant clinical activity, including observational studies and clinical trials (both industry and investigator-initiated) at this and other centers.

There are a large number of collaborations with national and international researchers, and within the center itself with the Anatomic Pathology, Haematology, Medical Oncology, Clinical Biochemistry, Infectious Diseases, Immunology, Microbiology, Rheumatology, Traumatology, Rheumatology and Bone Metabolism, Endocrinology, Digestive Surgery and Intensive Care Medicine groups.


Renal, Metabolic and Cardiovascular Diseases Area Scientific Activity

2023

Cardiology

Nephrology and Hypertension, Vascular Pathology and Diabetes

Lipid Pathology: Clinical and Experimental (adult and child)

Cardiac and Vascular Surgery Associated Group

Urology Associated Group

TOTAL

PROJECTS

EU/NIH PROJECTS

3

4

//

//

//

7

ISCIII PROJECTS

6

31

4

//

//

41

CYBER PROJECTS

1

2

//

//

//

3

MINISTERIAL PROJECTS

1

6

//

//

//

7

ACM PROJECTS

//

2

//

//

//

2

AWARDS

//

//

//

//

//

//

UNOFFICIAL PROJECTS

8

28

4

//

6

46

OBSERVATIONAL STUDIES

1

2

2

1

2

8

TOTAL

20

75

10

1

8

114

CLINICAL TRIALS

EARLY PHASES (I, I/II, II)

2

4

1

//

3

10

LATE PHASES (II/III, III, III/IV AND IV/OTHER)

21

12

3

//

7

43

TOTAL

23

16

4

//

10

53



Renal, Metabolic and Cardiovascular Diseases Area Publications

2023

Total no. of publications

No. of publications with IF

Accumulated IF

Average annual IF

No. of journals in Q1

% of journals in Q1

No. of publications in Open Access

No. of Clinical Practice Guidelines

Cardiology

48

47

457,1

9,73

29

61,70%

33

5

Nephrology and Hypertension, Vascular Pathology and Diabetes

159

159

1585,9

9,97

105

66,04%

135

14

Lipid Pathology: Clinical and Experimental (adult and child)

23

23

114,7

4,99

9

39,13%

11

4

Cardiac and Vascular Surgery Associated Group

4

4

9,7

2,43

1

25,00%

4

0

Urology Associated Group

13

13

38

2,92

3

23,08%

7

1

RENAL, METABOLIC AND CARDIOVASCULAR DISEASES AREA

247

246

2205,4

8,97

147

59,76%

190

24



6.4.0-ÁREA RENALES-A-PUBLIS6.4.0-ÁREA RENALES-A-PUBLIS

List of the five most relevant publications of the Renal, Metabolic and Cardiovascular Diseases Area during 2023

Global Burden of Cardiovascular Diseases and Risks, 1990-2022.

Mensah GA, Fuster V, Murray CJL, Roth GA, Global Burden of Cardiovascular Diseases and Risks Collaborators (Ortiz A).

J Am Coll Cardiol. 2023 Dec 19.82(25):2350-2473.

PMID: 38092509

FI: 24,4


A mutual regulatory loop between miR-155 and SOCS1 influences renal inflammation and diabetic kidney disease.

Prieto I, Kavanagh M, Jimenez-Castilla L, Pardines M, Lazaro I, Herrero Del Real I, Flores-Muñoz M, Egido J, Lopez-Franco O, Gomez-Guerrero C.

Mol Ther Nucleic Acids. 2023 Dec 12.34:102041.

PMID: 37842165

FI: 8,8


Regulated cell death pathways in kidney disease.

Sanz AB, Sanchez-Niño MD, Ramos AM, Ortiz A.

Nat Rev Nephrol. 2023 May.19(5):281-299.

PMID: 36959481

FI: 41,5


Paradigm Shift: Cardiovascular Health in the Elderly-Beware of the Brain.

Fuster V, Turco JV, Cortes-Canteli M.

J Am Coll Cardiol. 2023 Mar 28.81(12):1214-1215.

PMID: 36948739

FI: 24,4


Molecular basis of normal and pathological puberty: from basic mechanisms to clinical implications.

Argente J, Dunkel L, Kaiser UB, Latronico AC, Lomniczi A, Soriano-Guillén L, Tena-Sempere M.

Lancet Diabetes Endocrinol. 2023 Mar.11(3):203-216.

PMID: 36620967

FI: 44,5

Gender Perspective in Renal, Metabolic and Cardiovascular Diseases Area

The Renal, Metabolic and Cardiovascular Diseases Area is made up of a group of professionals committed to respect and equality among its team members, which seeks to promote the professional development of all its personnel without discrimination based on gender or age.

6.4.0-ÁREA RENALES-B-GÉNERO6.4.0-ÁREA RENALES-B-GÉNERO


Renal, Metabolic and Cardiovascular Diseases Area Future Goals

  • Improve the prognosis of renal diseases through the development of new diagnostic and risk stratification tools, and new therapeutic strategies.
  • Improve the prognosis of metabolic diseases through the development of new diagnostic and risk stratification tools, and new therapeutic strategies.
  • Improve the prognosis of cardiovascular diseases through the development of new diagnostic and risk stratification tools, and new therapeutic strategies.
  • Implement new therapeutic and evaluation strategies for Urological Health Results.


Research Groups

  • Cardiology
  • Nephrology and Hypertension, Vascular Pathology and Diabetes
  • Lipid Pathology: Clinical and Experimental (adult and child)
  • Cardiac and Vascular Surgery Associated Group
  • Urology Associated Group